RNA Details
Disease Name
idiopathic pulmonary fibrosis
Tissue
lung
RNA Symbol
Cav1
RNA ID
RNA Type
mRNA
Alteration Pattern
histone hypomethylation
Species
mus musculus
Detection Methods
qRT-PCR; Immunoblot; MSP etc.
Target
NA
Pathway
NA
PubMed ID
Title
Epigenetic Regulation of Caveolin-1 Gene Expression in Lung Fibroblasts
Year
2016
Function
"Cav-1 gene silencing in lung fibroblasts is actively regulated by epigenetic mechanisms that involve histone modifications, in particular H3 lysine 4 trimethylation, whereas DNA methylation does not appear to be a primary mechanism."